KAT5

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KAT5

A gene on chromosome 11q13 that encodes a catalytic subunit of the NuA4 histone acetyltransferase complex (NuA4 HAC) involved in transcriptional activation of genes, principally by acetylating nucleosomal histones H4 and H2A. The NuA4 HAC may be required for activating transcription programmes of oncogene and proto-oncogene mediated growth induction, tumour suppressor-mediated growth arrest/replicative senescence, apoptosis, and DNA repair. Post-translational modifications include sumoylation, phosphorylation, ubiquination and autoacetylation.

References in periodicals archive ?

Haupt et al., "PLIP: fully automated protein-ligand interaction profiler," Nucleic Acids Research, vol.

Identification of Lutzomyia longipalpis Odorant Binding Protein Modulators by Comparative Modeling, Hierarchical Virtual Screening, and Molecular Dynamics

Linux supports connection to the Internet or any other network using TCP/IP or IPX via Ethernet, Fast Ethernet, ATM (in Alpha development), modem, HAM/packet radio (X.25 protocol), ISDN, token ring, or PLIP (modified printer cable to another computer).

Revenge of the clone operating system

There are a million gumnuts on this goddam tree, I've pulled the caps off hundreds and I can't find the bloody things: dear little Chucklepot and Gurglepie and Silly Lilly-Pilly and Piddlepot and Puddlepie and Plip and Plop .

Biddy the Baglady in Gumnut land

Thanks to funding from the Bill & Melinda Gates Foundation, eIFL.net's Public Library Innovation Project (PLIP) will distribute up to $465,000 in grants and awards over the next 3 years for the purpose of expanding the capabilities of public libraries in the third world.

Innovation project accepting proposals

Plip the key fob and lights come on to guide you to your car.

Motors: A BALLET GOOD WAY TO DODGE THE WEATHER; ROAD TEST Volkswagen Eos Sport 2.0T

Plip a button on the remote fob and the doors slide open.

Opening a door into the future

With its plip activated remote locking, engine immobiliser, laminated side windows, deadlocks, ultrasonic alarm, and locking wheel nuts, it beat 81 rivals to take the title

Driving Seat: Plugs & POINTS

WHAT HAPPENS Adults and Personal Life Policies Own, Not Orphans 39% Lapse, Cancel 9% Never owned PLIP 36% Orphans 16% Note: Table made from pie chart.

Direct marketing to policyholders: a 'win-win' for carrier and broker: there are more orphaned policyholders than most data suggest

To be called the Peugeot 1007, it is a four-seater with access to the rear via the sliding doors, which are operated by a plip on the key fob.

Peugeot perfect when you're in a tight spot

The driver can release the boot lock by pressing a button on the remote plip while approaching the car and it will open by the time they get to it.

Road test: Rover 45: Saving face; Rover designers have not allowed a tight budget to stop them from doing a great job on the new 45, says Bill Caven

The site is really set up for techies and is way above my head - for instance, "connection to the net is via PLIP".