Platelets


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platelets

[plat′lits]
Etymology: Fr, small plate
anucleate blood cells, 1-3 μm in diameter. Platelets are formed from bone marrow megakaryocytes. Approximately one third of circulating platelets become temporarily sequestered in the spleen. Platelets are disk-shaped, contain no hemoglobin, and are essential for coagulation and in maintenance of hemostasis. The platelet count reference interval is 150,000-450,000/uL. Also called thrombocyte. Compare erythrocyte, leukocyte. See also thrombocytopenia, thrombocytosis.
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Platelets

blood platelets

or

platelets

or

thrombocytes

disc-like components of mammalian BLOOD, consisting of non-nucleated cytoplasmic fragments of large bone-marrow cells 3 μm in diameter called megakaryocytes that have entered the blood circulatory system. Platelets play an important part in BLOOD CLOTTING.

Platelets

Fragments of a large precursor cell (a megakaryocyte) found in the bone marrow. These fragments adhere to areas of blood vessel damage and release chemical signals that direct the formation of a blood clot.

platelets

syn thrombocytes cellular fragments in the blood, involved in blood coagulation. Platelets aggregate and adhere to form a temporary plug at the site of blood vessel damage.
References in periodicals archive ?
The test can be used to extend the dating of apheresis platelets in plasma, the most common platelet type transfused in the US, from five to seven days.
CD62p and CD63 percent positivity of pre- and post-apheresis platelets showed significant changes and statistically significant difference (p=0.
The mean automated optical platelet count estimate was 40[+ or -]30 x [10.
The correlation with the ischemic strokes is well established secondary to increased responsiveness of larger younger platelets with increased MPV18-20, and the known beneficial effects of using antiplatelet therapeutic strategies in preventing ischemic stroke21.
Only dengue seropositive cases who have been platelet transfused were included in the study.
Table-II: Platelets parameters in ITP, Non-ITP patients and normal individuals.
Rapid assessment of platelet production may aid clinicians in distinguishing between thrombocytopenia due to platelet destruction (such as immune thrombocytopenia [ITP]) and low platelet count due to aplastic disorders or other bone marrow failure syndromes.
An increase in the number of young platelets and in MPV is expected with activation of platelets in case of inflammation.
In the diagnostic approach to refractoriness to platelet transfusion a CCI at one hour of >7,500 platelets x [m.
To achieve a larger surface area, platelets modify their shapes during activation.
Unlike other sources of platelets, company officials said, human Induced Pluripotent Stem Cells can be propagated indefinitely, providing a potentially unlimited source of cells for therapeutic purposes.
Blood cells, such as platelets, are made in bone marrow.