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It replaces an antibody obtained from mice in Cuba's manufacturing of the hepatitis B vaccine, researchers said, Carlos Borroto, deputy director at Cuba's Biotechnology and Genetic Engineering Center (CIGB) here, said the plantibody won approval from Cuba's medication quality control agency.
Assuming that a 10-mg dose of antibody is protective (i.e., assuming that the mAb is only 100-fold more potent than polyclonal preparations [118]), the production costs for the amount of plantibody needed for 100 days of protection could be approximately one cent (102).
Ma of Guy's Hospital in London and his colleagues described the first use of a plantibody in people.