piperazine

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Related to Piperazines: TFMPP

piperazine

 [pi-per´ah-zēn]
an anthelmintic used in various salts against Ascaris lumbricoides and Enterobius vermicularis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pi·per·a·zine

(pī-per'ă-zēn, -zin),
A veterinary anthelmintic and filaricide.
Synonym(s): diethylenediamine
Farlex Partner Medical Dictionary © Farlex 2012

piperazine

(pī-pĕr′ə-zēn′, pĭ-)
n.
1. An organic compound, C4H10N2, that is used (often in the form of a salt) as an anthelmintic in humans and domestic animals and is widely used in the manufacture of pharmaceuticals, synthetic resins, polyurethane, and other industrial products.
2. Any of various derivatives of this compound, some of which have stimulant and hallucinogenic properties.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

piperazine

An ANTHELMINTIC drug used to get rid of ROUNDWORMS and THREADWORMS. The drug paralyses the worms which are then passed with the faeces. A brand name for the drug formulated with the laxative senna is Pripsen.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

pi·per·a·zine

(pī-per'ă-zēn, -zin)
A veterinary anthelmintic and filaricide.
Synonym(s): diethylenediamine.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
The piperazine derivatives most frequently consumed as recreational substances are BZP (1-benzylpiperazine), MDBP 1-(3,4-methylenedioxy benzyl) piperazine, TFMPP (3-trifluoromethylphenyl) piperazine and MeOPP 1-(4-methoxyphenyl) piperazine.
Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.
Maarseveena, Synthesis of 2-Substituted Piperazines Via Direct a- Lithiation, Tetrahedron Lett., 46, 2369 (2005).
The S- and N,S-substituted trichlorobutadienes could be obtained from the reactions of polyhalonitrobutadienes We have prepared N,S-substituted trichlorobutadienes from the reaction of some S-substituted nitrobutadienes with piperazine derivatives [4-9].
The piperazine protons of the substituted compounds 5c, 7c, 9c, 11a and 13c have been observed as multiplets around 3.51-3.67 ppm.
We saw that the peaks of piperazine methylene groups were broad signals at d = 3.54-3.63 ppm and singlet at d = 3.79-3.86 ppm at room temperature.
The docking of acetyl-cholinesterase was performed against piperazine derivatives by using Autodock 4.2 (http://autodock.scripps.edu/wiki/ AutoDock4/), a novel and robust automated docking method.
1-(1,4-Benzodioxane-2-carbonyl) piperazine (K) was synthesized from 1,4-benzo dioxan-2-carbonyl chloride with piperazine in dry DMF at 80[degrees]C for 8 h.
The data obtained from biological evaluation done by Ellman's method, the piperazine derivatives exhibited AChE inhibitory activity in a concentration dependent manner.
First 1-(4-methoxyphenyl) piperazine were generated in situ from diethanolamine using one-pot synthesis method.1-(4-methoxyphenyl)piperazine react with p-chloronitrobenzene to synthesize 1-(4-methoxyphenyl)-4-(nitrophenyl) piperazine by N-arylation.
The crude product followed by its reaction with p-anisidine, without isolation treatment,can be carried out in one pot to obtain 1-(4-methoxyphenyl) piperazine in order to avoid purification carcinogenic bis(2-chloroethyl)amine.
A mixture of 0.07mol 1-(4-methoxyphenyl) piperazine dihydrochloride, 0.073mol 1-chloro-4-nitrobenzene, 0.12mol potassium carbonate, 50ml N,N-Dimethylformamide is stirred and refluxed for 24h at 110[degrees]C.