Pick disease


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Related to Pick disease: Pick bodies, hydrocephalus ex vacuo

Pick dis·ease

(pik),
progressive circumscribed cerebral atrophy; a rare type of cerebrodegenerative disorder manifested primarily as dementia, in which there is striking atrophy of portions of the frontal and temporal lobes. Synonym(s): Pick syndrome
[F. Pick]

Pick disease

n.
Variant of Pick's disease1.

Pick dis·ease

(pik di-zēz')
Progressive circumscribed cerebral atrophy; a rare type of cerebrodegenerative disorder manifested primarily as dementia, in which there is striking atrophy of portions of the frontal and temporal lobes.
[F. Pick]

Pick,

Friedel, German physician, 1867-1926.
Pick atrophy - Synonym(s): Pick disease
Pick bodies - intracytoplasmic argentophilic inclusion bodies seen in neurons in Pick disease.
Pick disease - a rare type of cerebral degenerative disorder manifested primarily as dementia. Synonym(s): Pick atrophy; Pick syndrome; progressive circumscribed cerebral atrophy
Pick syndrome - Synonym(s): Pick disease
References in periodicals archive ?
These corticobasal bodies can be stained with Gallyas, are tau-4R immunoreactive, and are found mostly in the frontal and parietal cortex, in contrast to Pick bodies in Pick disease. A dominant, and in the case of CBD a characteristic, finding are numerous Gallyas- and tau-immunoreactive threads in the neuropil of affected gray matter structures and adjacent white matter.
Pick disease showing granular neurons of the dentate fascia of the hippocampus with tau- immunoreactive cytoplasmic inclusions (a).
The rest of the 23.07% cases were storage disorders which included Neimann Pick disease and Gaucher's disease.