physical map


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phys·i·cal map

a map of a stretch of DNA with ordered landmarks a known distance from each other; the ultimate physical map would be the base sequence of the entire chromosome.

phys·i·cal map

(fiz'i-kăl map)
A map of a stretch of DNA with ordered landmarks a known distance from each other; the ultimate physical map would be the base sequence of the entire chromosome.

physical map

(of genome) a map consisting of an ordered set of DNA fragments representing the genome or a particular, localized genomic region. A physical map may be a restriction map, comprising of an ordered set of DNA fragments generated by using RESTRICTION ENZYMES. The map indicates the position and number of restriction sites for specific enzymes. For large genomes, restriction enzymes that cleave the DNA infrequently are used to generate large restriction fragments that can be ordered in a macro-restriction map. An ordered clone map, or clone contig map consists of an overlapping collection of cloned DNA fragments comprising all the DNA of the genome or part of the genome.See CLONE CONTIG SEQUENCING METHOD.

physical

pertaining to the body, to material things, or to physics.

physical agent
the physical causes of disease. Includes altitude, radiation, wetness, exercise, fire, electricity including lightning.
physical diagnosis
a preliminary diagnosis made solely on the basis of a physical examination. Often all that is possible in private practice.
physical examination
examination of the bodily state of a patient by ordinary physical means, as inspection, palpation, percussion and auscultation.
physical exhaustion
see physical exhaustion.
physical findings
results of a physical examination. Observations made visually, by auscultation, palpation, smell, percussion, succussion and ballottement.
physical fitness
quality of being able to perform physically, to turn in a good physical performance. Best tested by performance but in horses can be vaguely predicted by a series of tests including hemoglobin content of blood, heart size, duration of the QRS interval on an ECG, and low levels of muscle enzymes in blood.
physical insults
physical agencies that cause disease. These include trauma, stress (physical as in stress fracture of long bones in horses), hyperthermia (as a cause of congenital defects), persistent wetting, high altitude, lightning stroke, electrocution, bushfire and fire injury, volcanic eruption and exposure to radiation.
physical map
in genetics, determination of the array of genes within a DNA segment of a chromosome.
physical restraint
the use of halters, collars and chains, ropes, harness, twitches of various sorts, squeeze cages, hog holders, dog catchers and many more devices. As distinct from the use of analeptic agents—chemical restraint.
physical stress
see stress.
physical therapist
one who is skilled in the physical and therapeutic techniques of helping to alleviate suffering from muscle, nerve, joint and bone diseases and from injuries and to overcome or prevent disabilities. Among the procedures used by the physical therapist are exercise to increase strength, endurance, coordination, and range of motion; electrical stimulation to activate paralyzed muscles; massage, vibrators and many other patented devices to try to improve the circulation and condition of a part. Called also physiotherapist.
References in periodicals archive ?
The cytological approach used here allowed to obtain the first integrated physical map of C.
To construct the physical map of Psm, PFGE analysis of independent digestions with restriction enzymes PacI, PmeI and SwaI of wild type Psm chromosomal DNA were performed.
Using a physical map of Argentina, have students locate three places or regions through which the Tropic of Capricom passes.
The ability to use this rapid labeling technology enabled the French scientists to perform the extensive series of experiments required to complete a first-generation physical map of the genome in record time
On the basis of the physical map data, the sequence based on recombinants 5 and 6 is clearly wrong.
The sites of cleavage were also used as landmarks on the genome, thus giving a physical map.
Physical maps will convey location more precisely by showing the actual distance between genes.
In preliminary studies, we mapped to chromosome 4 of Geneva a 5 cM region containing three genes conferring both dominant and recessive scab resistance, which corresponds to a 2 Mbp region containing nine candidate NBS-LRR resistance genes on the physical map of Golden Delicious (GD).
A primary goal of the Maize Mapping Project (MMP) is to develop an integrated genetic and physical map of maize to enable the cloning of maize genes controlling phenotypes and crop productivity.
The BAC physical map will be a useful tool for identifying genes that affect production traits and could act as the backbone for future efforts to sequence the catfish genome.
Towards a cytogenetically based physical map of the wheat genome.

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