phthalic acid

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phthal·ic ac·id

(thal'ik as'id),
o-Benzenedicarboxylic acid.
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References in periodicals archive ?
A series of N-aryl phthalimides was prepared through the reaction of phthalic acid with aryl amines (anilines) in ethanol under mild condition with L-proline as catalyst at room temperature.
Phthalimides 1-7 were biologically evaluated for their anti-inflammatory, antioxidant, and lipoxygenase enzyme inhibition activities.
Phthalimide 2, 3, and 5-7 showed weak DPPH radical scavenging activity, while phthalimide 1 and 4 showed strong activity with [IC.sub.50] values 21.34 and 20.45 [micro]M, respectively, which has much better potential as compared to the standard BHA ([IC.sub.50] = 44.2 [micro]M).
In this study, the protein denaturation bioassay was performed for in vitro assessment of anti-inflammatory activity of phthalimide derivatives.
Reagent Phthalimide Thalidomide Thiourea 59% 40% DMAP N[H.sub.4]Cl 57% 43% Ammonium acetate 90% 7%
Ismail, "Effects of non-ionic and mixed cationic--non-ionic micelles on the rate of alkaline hydrolysis of phthalimide," Journal of Physical Organic Chemistry, vol.