photosensitizer

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photosensitizer

Oncology A substance that sensitizes an organism, cell, or tissue to light; an agent used in photodynamic therapy which, when absorbed by CA cells and exposed to light, is activated, killing cancer cells. See Photodynamic therapy.

photosensitizer

(fō″tō-sĕn′sĭ-tī″zĕr)

A substance that, in combination with light, will cause a sensitivity reaction in the substance or organism.

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PDT is performed by first administering to the patient a photosensitizing agent, which is usually given intravenously but can also be given orally or applied topically.

The perfect photosensitizing agent would be a single compound with high tumor selectivity and increased absorption of the red region of light in the treatment area for deeper tissue penetration.

The efficacy of photodynamic therapy in the treatment of oral squamous cell carcinoma: a meta-analysis

Topical or systemic photosensitizing agents include drugs (e.

Natural therapeutics: anti-photoaging

PDT involves the administration of a photosensitizing agent that localizes in areas of high cellular and vascular growth.

Are two photons better than one? Two-photon excitation is a new paradigm in photodynamic therapy, and Canadian research is on top of the latest developments. (Articles)

Current AMD therapies: Current role in the AMD market for angiostatic steroids, photosensitizing agents, VEGF inhibitors, and combination therapy.

The FDA Raises Safety Concerns Regarding Off-Label Use of Avastin for Age-Related Macular Degeneration through Repackaging Avastin into Syringes for Intravitreal Delivery