21 mm) compared with SRP alone, although the ADA found a moderate level evidence supported the use of the PDT DL in conjunction with a photosensitizing agent
The perfect photosensitizing agent
would be a single compound with high tumor selectivity and increased absorption of the red region of light in the treatment area for deeper tissue penetration.
First degrease the skin, then apply the photosensitizing agent
under plastic wrap occlusion for 1-3 hours with low-level blue light, and apply 5%-7% topical lidocaine 30 minutes before putting on the red PDT light for 10-30 minutes.
PDT involves the administration of a photosensitizing agent
that localizes in areas of high cellular and vascular growth.
Researchers are also looking at different laser types and new photosensitizing agents
that may increase PDT's effectiveness against cancers located deep inside the skin or within an organ.
At least two companies are developing photosensitizing agents
for acne treatment, and there are already initial reports suggesting the approach may have some utility.