photosensitizer

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photosensitizer

Oncology A substance that sensitizes an organism, cell, or tissue to light; an agent used in photodynamic therapy which, when absorbed by CA cells and exposed to light, is activated, killing cancer cells. See Photodynamic therapy.

photosensitizer

(fō″tō-sĕn′sĭ-tī″zĕr)
A substance that, in combination with light, will cause a sensitivity reaction in the substance or organism.
References in periodicals archive ?
Each photosensitizer is activated at a unique excitation wavelength, and photosensitizers now in clinical trials are activated at longer wavelengths, offering slightly deeper tissue penetration.
The effect of Sn(IV) chlorin e6 on the viability of HepG2 was less than effect of other photosensitizers such as 5-ALA and PAD-S31 which reached 80% of phototoxicity, while this photosensitizer did not exceed 50% at the indicated concentrations and doses.
Histomorphological changes in murine fibrosarcoma after photodynamic therapy (PDT) based on the natural photosensitizer hypericin were evaluated.
Triplet oxygen is a good energy acceptor and it can be excited to its singlet state by energy transfer from a photosensitizer.
On the basis of types, the global drug device combination products market is classified into infusion pumps, drug eluting stents, orthopedic combination products, photosensitizers, inhalers, wound care combination products, transdermal patches, and other drug device combination products.
Objective: Charge transfer (CT) processes play an important role in photosensitizers and photocatalytic reactions that have found great potential in solar energy conversion and enviromental remediation.
According to a new market report published by Transparency Market Research " Drug Device Combination Products Market (Drug Eluting Stents, Infusion Pumps, Photosensitizers, Orthopedic Combination Products, Wound Care Combination Products, Inhalers, Transdermal Patches, Intraocular Implants and Drug Eluting Beads)- Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019 ," the global drug device combination productsmarket was valued at USD 66.
It provides a solid understanding of the design, delivery, and dosimetry of the three basic ingredients of PDT: photosensitizers, light, and oxygen.
The type of molucules that can act as photosensitizers in biological systems is very large.
When the photosensitizers are activated by the laser light, they produce a form of oxygen that destroys illuminated cancer cells.
Yet, only five photosensitizers are now approved for clinical applications and all suffer from serious drawbacks, including low selectivity and skin sensitization.
2) studied the production of singlet oxygen of the substituted photosensitizers difurnonaphthalene and distyryl benzene.