For the polarization sensitivity, the researchers essentially copied the way the mantis shrimp integrates polarized light detection into its photoreceptors
by depositing nanomaterials directly onto the surface of the imaging chip that contained photodiodes.
The therapy is an attempt to shore up the health of remaining photoreceptors
by replacing dying RPE with iPSC-derived RPE.
are specialized neurons that comprise the light-sensing cells of the retina, an extension of the central nervous system located at the back of the eye.
Apparently they divide in response to injury and are able to convert into photoreceptors
as well as other retinal neurons, making it possible to restore vision in the fish after severe retinal injury.
If rods can be regenerated from inside the eye, this might be a strategy for treating diseases of the eye that affect photoreceptors
Macular degeneration, an incurable eye disease that results in significant vision loss starting on average in a person in his 50s or 60s, is the death of photoreceptor
cells in the retina.
precursor cells derived from embryonic stem cells can be transplanted in adult mouse models of retinal degeneration that still have dysfunctional photoreceptor
layer (or outer nuclear layer).
"We demonstrate OCT evidence of localized pathological changes at the level of the photoreceptors
in small lesions among survivors of EVD with retinal lesions," the authors write.
Scientists at the University of Queensland in Australia have discovered a new type of cell that displays properties of both rod and cone photoreceptor
More importantly, these retinal organoids could achieve a high degree of maturation with formation of outer segment discs, functional structures of light-sensing photoreceptors
, which was first reported by Zhong et al.
Retinitis pigmentosa (RP) is a group of heterogeneous inherited photoreceptors
' apoptosis and retinal degeneration disease characterized by constricted visual fields and photoreceptor
cell dysfunction .
The new research involved reprogramming surviving non-light sensitive cells in the retina to convert them into new photoreceptors