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Choline O-phosphate; important in choline metabolism, for example, in the biosynthesis of lecithins.
Synonym(s): phosphorylcholine


(fŏs-fō-kō′lĭn, lēn) [Fm. phospho(rus) + ″],


A choline metabolite.
References in periodicals archive ?
Supply of a phosphorylcholine coating oxygenator with a tubular set.
IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus: Regulation and underlying mechanisms.
Phosphorylcholine, unlike the other drug compounds used previously, is exclusively meant to prevent coronary artery blockage.
In addition, other studies have shown that CK and phosphorylcholine (PCho) production are increased in growth factor-induced mitogenic signaling of primary human breast epithelial cells in response to insulin or hydrocortisone (4).
Frostegard, "Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study," Arthritis Research & Therapy, vol.
[12] prepared the multifunctional phosphorylcholine/peptide (PC/PT) coating containing phosphorylcholine groups and endothelial progenitor cell- (EPC-) specific peptides on Ti surfaces via dip coating technique and found that the PC/PT coating not only manifested greatly enhancement in blood compatibility, but also induced considerable enhancement in EPC adhesion and proliferation, substantially hindering smooth muscle cell adhesion and proliferation.
Meanwhile, the characteristic signals of nitrogen-containing metabolites, such as choline, phosphorylcholine, and betaine, were clearly observed in this region, as shown in Table 1.
Cer is also a precursor for the synthesis of SM by the SM-synthase that exists in 2 isoforms SM-synthase 1 and SM-synthase 2, by adding to Cer the phosphorylcholine (PPC) of phosphatidylcholine (PC) [1].
A facile technique for fabricating poly (2-methacryloyloxyethyl phosphorylcholine) coatings on titanium alloys--Chang Wu, Weiyuan Chang, Hongzhao Qi, Lixia Long, Jin Zhao, Xubo Yuan, Zhaoyang Li, and Xianjin Yang
On the other hand, it increases the level of natural antibodies against Phosphorylcholine (PC).
It is possible that its chemical composition of sphingomyelin, phosphorylcholine, and ceramides somehow prevents carotenes from being deposited, or the minute amounts present are grossly imperceptible.
In recent years co-polymers have been incorporated into the soft hydrogel lens materials, including silicone polymers for increased oxygen permeability and phosphorylcholine to increase biocompatibility (Willcox et al., 2001).

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