phosphohexose isomerase


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glu·cose-phos·phate i·som·er·ase

(glū'kōs-fos'fāt ī-sō'mĕr-ās),
An enzyme that catalyzes the interconversion of d-fructose 6-phosphate and d-glucose 6-phosphate; a part of glycolysis and gluconeogenesis; glucosephosphate isomerase deficiency is an inherited disorder resulting in liver glycogenesis and hemolytic anemia.
Farlex Partner Medical Dictionary © Farlex 2012

phosphohexose isomerase

(1) Mannose-6-phosphate isomerase, EC 5.3.1.8.
(2) Glucose-6-phosphate isomerase, EC 5.3.1.9.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Phosphohexose Isomerase (PHI) is reported to be a dimeric enzyme involved in glycolysis (Cooke and Buckley, 1987).
The components are (1) tumor markers: HCG-lntact Hormone by IRMA, HCG-Total Hormone (intact, nicked intact, free [beta], nicked, and free [beta], fragments) by chemiluminescence, HCG-Urine test by chemiluminescence, PHI enzyme (phosphohexose isomerase or glucose phosphate isomerase) by enzyme kinetics, and CEA (carcinoembryonic antigen) by chemiluminescence; and (2) peripherally related assays: GGTP, TSH, and DHEA-S.
PHI: Phosphohexose isomerase, EC 5.3.1.9, is also known as glucose phosphate isomerase or phosphoglucose isomerase, and was originally isolated from a human melanoma cell line.
Enzyme activity Ensyme C2-4 (normal) Ex139 (hls) units [g.zup.-1] protein Amylase 34.7 35.3 Starch phosphorylase 15.7 15.3 Hexokinase 0.95 1.01 Phosphoglucomutase 0.84 0.80 Phosphohexose isomerase 1.88 1.87 Phosphofruetokinase 0.84 0.83 Aldolase 6.9 6.5 Triosephosphate isomerase 125 126 Fructose-1,6-bisphosphatase 2.8 2.7 UDP glucose pyrophosphorylase 0.5 0.5 Sucrose-P phosphalase 18 17 Invertase 61.4 87.3 Significance Ensyme of t-test Amylase NS Starch phosphorylase NS Hexokinase NS Phosphoglucomutase NS Phosphohexose isomerase NS Phosphofruetokinase NS Aldolase NS Triosephosphate isomerase NS Fructose-1,6-bisphosphatase NS UDP glucose pyrophosphorylase NS Sucrose-P phosphalase NS Invertase (**) (*), (**) means significantly different at P = 0.05 and P = 0.01, respectively.

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