A 50 [micro]l aliquot was used for Agilent 6410B Triple Quadrupole LCMS testing to analyze sphingolipids, and another 50 [micro]l was used for Thermo Scientific HPLC-LTQ/FTICRMS testing to analyze phosphoglycerides, glycerides and sphingomyelins.
LC-MS conditions for sphingolipids, phosphoglycerides, glycerides and sphingomyelins were previously established (Qu et al.
The neurotoxins have phospholipase A2 activity and hydrolyze phosphoglycerides
thereby producing neuromuscular blockade by inhibiting the release of acetylcholine from the presynaptic membrane.
Evidence that the basal turnover of phosphoglycerides
does not involve phospholipase D," Journal of Biological Chemistry, vol.
(1979) Metabolism of arachidonoyl phosphoglycerides
in mouse brain subcellular fractions.
n-3 and n-6 polyunsaturated fatty acids in the phosphoglycerides
of salt-secreting epithelia from two marine fish species.
Distribution and fatty acid composition of phosphoglycerides
in normal human brain.
Phospholipids with a glycerol backbone are known as glycerophospholipids or Phosphoglycerides
. In all phosphoglycerides
, there are two fatty acid chains and one Phosphorylated alcohol functionality on a glycerol backbone.
Total fatty acids, plasmalogens, and fatty acid composition of ethanolamine and choline phosphoglycerides
. Journal of Neurobiological Research 20:484-490.
These compounds originate from transmethylation of 1-alkenyl chains of plasmalogens, a type of ether-containing phosphoglycerides
found in animal membrane cells.
Altered composition of polyunsaturated fatty acyl groups in phosphoglycerides
of Down's syndrome fetal brain.
(8) Plasmodium is incapable of de novo synthesis of fatty acids and cholesterol; but it can fabricate its glycerides and phosphoglycerides
with host-supplied nutrients, and can produce the glyceryl moiety during glycolysis.