Commercial lecithin is a mixture of several natural phospholipids (phosphatidyl choline, phosphatidyl inositol, phosphatidyl ethanolamine
, and phosphatidic acid) in oil.
The methyltransferase genes were arsenic(+III oxidation state) methyltransferase (AS3MT), DNA-methyltransferase la and 3b (DNMT la and DNMT3b), phosphatidyl ethanolamine
N-methyltransferase (PEMT), and betaine-homocysteine methyltransferase (BHMT).
(PE), phosphatidyl choline (PC), phosphatidyl inositol (PI) phosphatidyl serine (PS), sphingomyelin (SPH) and lysophosphatidyl choline (LPC), fatty acids C14:0, C14:1, C16:0, C17:0, C18:0, C18:1, C18:2, C18:3, C20:4, C22:4 and C22:6 standards were bought from Sigma-Aldrich Chemical Co.
Junovan (mifamurtide - Liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine
MTP-PE) is selectively delivered to marcrophages via the scavenger lipoprotein receptor pathway, activating the tumoricidal activity through the cytoplasmic Nod2 receptor.
The selected genes for ACP ddRT-PCR analysis validation were insulin like growth factor 3, phosphatidyl ethanolamine
binding protein, ATP synthase F0 and complement component CD.
Mepact (Mifamurtide - Liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine
, L-MTP-PE) is a fully synthetic lipophilic derivative of muramyl dipeptide.
Junovan (Mifamurtide - Liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine
, MTP-PE) is a fully synthetic lipophilic derivative of the muramyl dipeptide.
Nasdaq:EPMN), announces that the Phase III clinical results for its Liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine
product (L-MTP-PE), also named Mepact(TM), will be presented and discussed in a panel symposium on May 16 in Washington, DC.