Regulated internalization and phosphorylation of the native norepinephrine transporter in response to
phorbol esters. Evidence for localization in lipid rafts and lipid raft-mediated internalization.
However, Makkar and Becker [5] reported that the presence of a cocktail of anti-nutritional factors like
phorbol esters, saponins, tannins, phytates, lectins, hydrocyanides and oxalates prevent its use in animal feeding;
phorbol ester is considered the most toxic compound.
curcas cake possesses antinutritional and toxic factors, such as curcin and
phorbol esters, that limit the use of the cake in food [9].
"Potential of Using
Phorbol Esters as an Insecticide against Spodoptera Frugiperda." Industrial Crops and Products 38 (July): 50-53.
cannot be utilized as animal feed due to the presence of toxic
phorbol esters. However biological treatments may alleviate the concentration of
phorbol esters to a safe level.
will receive complete ownership and all interest in the indication, patents and intellectual property related to treatment of Hodgkin's Lymphoma, utility patent application number 61998397, entitled 'Compositions and methods of use of
Phorbol Esters for the treatment of Hodgkin's Lymphoma'.
Jatropha curcas is a non-edible vegetable oil due to the presence of
phorbol esters which accounts for its toxicity.
Vlietinck, "[sup.13]C NMR spectroscopy of
phorbol esters," Magnetic Resonance in Chemistry, vol.
Not content just to cause pain and blindness, the plant has long-term ideas as well: it contains
phorbol esters, which are not only skin irritants but actually promote cancer development, suppress the immune system and activate dormant Epstein-Barr virus.
Tumor-promoting
phorbol esters induce metamorphosis and multiple head formation in the hydroid Hydractinia.
TPA, a kind of
phorbol esters, is one of the main irritant compounds in Euphorbiaceae plants.
Phytochemical studies of members of the family Euphorbiaceae revealed the presence of flavonoids, saponins, diterpenes, and
phorbol esters (Bagalkotkar et al., 2006; Jassbi, 2006).
