phenylacetic acid

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phenylacetic acid

 [fen″il-ah-se´tik]
a catabolite of phenylalanine; it is excessively formed and excreted, sometimes conjugated with glutamine, in phenylketonuria.

phen·yl·a·ce·tic ac·id

(fen'il-ă-sē'tik as'id),
An abnormal product of phenylalanine catabolism, appearing in the urine of patients with phenylketonuria.

phenylacetic acid

/phen·yl·a·ce·tic ac·id/ (fen″il-ah-se´tik) a catabolite of phenylalanine, excessively formed and excreted in the urine in phenylketonuria.

phenylacetic acid

[fen′iləsē′tik]
a catabolite of phenylalanine, excessively formed and excreted, sometimes conjugated with glutamine, in phenylketonuria.

phen·yl·a·ce·tic ac·id

(fen'il-ă-sē'tik as'id)
An abnormal product of phenylalanine catabolism, appearing in the urine of people with phenylketonuria.
References in periodicals archive ?
To make an abzyme that specifically cleaves phenylacetate, the researchers obtained antibodies that bind to another longer-lived molecule that is similar in form to phenylacetate's fleeting transition-state.
The colonies were negative for nitrate reduction to nitrite, oxidase, indole production, gelatin hydrolysis, N-acetyl-D-glucosamine; and assimilation of arabinose, mannose, maltose, caprate, adipate, citrate, and phenylacetate.
Phenylacetate was used as the substrate in these assays, and hydrolysis rates were reported in units per milliliter.
A further modification of the salt-stimulation technique combined the salt-stimulation technique with the differential inhibition of the phenylacetate (PA) hydrolysis by 0.
We measured three PON1 enzyme activities in plasma from mothers and children, using paraoxonase (POase), chlorpyrifos oxonase (CPOase), and phenylacetate arylesterase (AREase) according to published protocols (Jarvik et al.
To prevent an ammonia spike during Yang's labor on November 17, 2009, Enns and his colleagues put part one of their plan in motion, first infusing a solution of sodium phenylacetate and sodium benzoate, along with arginine hydrochloride, into Yang's bloodstream to safely capture the toxin.
Moreover, we measured the activity of PON1 with paraoxon as substrate, whereas the previous study (5) used phenylacetate as a substrate.
PON1 activity was assessed by measuring the hydrolysis of phenylacetate (added to plasma) to acetic acid and phenol, as previously described (Chen et al.
In addition, different forms of the enzyme have different substrate specificities toward organophosphates, which they do not exhibit toward phenylacetate.
The level of PON 1 activity in each blood sample was determined by an assay that measures hydrolysis of phenylacetate.
PON1 activity was determined by use of phenylacetate as substrate (11).