fen-phen

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fen-phen

(fĕn′fĕn′)
n.
A combination of two drugs, fenfluramine hydrochloride and phentermine, formerly prescribed for weight loss but withdrawn from the market in 1997 because of potentially dangerous side effects.

Fen-Phen

Cardiology A once-popular combination of 2 anorectic agents, fenfluramine and phentermine; the theoretical advantage of using 2 different agents is that the dose of each agent could be lowered Adverse effects The fen-phen combination is associated with valvular heart disease and fatal pulmonary HTN; it was withdrawn from the market. See Fenfluramine.
References in periodicals archive ?
It's not likely that there will ever be a perfect pill, but one new drug, reported in the January 20, 1999, JAMA, at least offers the promise of aiding a balanced weight-loss program when combined with modified eating habits and exercise--without damaging the heart or lungs, as with the phen-fen drugs of yore.
PHEN-FEN, was licensed in America but then withdrawn last September after it was linked with heart valve defects.
The suit, filed last Friday, alleges that Cunningham and Gallion, both in jail awaiting trial in a fraud case relating to a class action suit regarding the diet drug phen-fen, owe McPeek a five per cent commission on the private sale of Curlin after the horse's debut in February.