Fen-Phen

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fen-phen

(fĕn′fĕn′)
n.
A combination of two drugs, fenfluramine hydrochloride and phentermine, formerly prescribed for weight loss but withdrawn from the market in 1997 because of potentially dangerous side effects.

Fen-Phen

Cardiology A once-popular combination of 2 anorectic agents, fenfluramine and phentermine; the theoretical advantage of using 2 different agents is that the dose of each agent could be lowered Adverse effects The fen-phen combination is associated with valvular heart disease and fatal pulmonary HTN; it was withdrawn from the market. See Fenfluramine.

Fen-Phen

(fen´-fen´),
n a combination of fenfluramine hydrochloride and phentermine hydrochloride, two stimulants, which promotes weight loss by reducing appetite. It is no longer available due to its damaging of the heart's valves. Thus it is important for a patient who has a history of using this medication to get a cardiac screening to check for risk of bacterial endocarditis. See also fenfluramine hydrochloride and phentermine hydrochloride.
References in periodicals archive ?
The suit, filed on behalf of Papeika's husband and two children, claims drug-maker Wyeth knew phen-fen caused primary pulmonary hypertension (PPH), a lethal condition.
Since 1999, American Home Products has paid more than $16 billion to settle claims brought by phen-fen users and their families.
Even though phen-fen has been off the market for years, there are still people dying from it.
compared to the untreated group (Redux 0 percent; phen-fen 4.
In addition, there were no cases of endocarditis (infection of the heart valve) or heart valve surgery following treatment with Redux or phen-fen.
Pulmonary hypertension is a family of life-threatening diseases of high blood pressure between the heart and the lungs, including Primary Pulmonary Hypertension (PPH), a disease which has been associated with diet drugs Redux and Phen-Fen.
Genetic Evolutionary Nutrition's GEN-FEN is the nation's most popular 100 percent safe and natural alternative to the Phen-Fen Diet.
GEN-FEN mimics the properties of Phen-Fen but is not structurally related to its now-banned cousin.
SALT LAKE CITY--(BUSINESS WIRE)--July 14, 1997--While the medical community debates the safety of the prescription weight-loss drug Phen-Fen, a combination of natural amino acids including DL-Phenylalanine is being hailed by nutritionists, counselors and users alike as an extremely effective tool against the major causes of weight gain - cravings and binging.
PhenCal 106, a dietary supplement containing the patented amino acid combination long used to combat drug and alcohol addictions, is clinically proven to be as effective as Phen-Fen without the negative side effects(a).
LOS ANGELES--(BW HealthWire)--June 30, 1997--The Herbal Phen-Fen wave has been sweeping the nation now that Genetic Evolutionary Nutrition (GEN) has announced the release of GEN-FEN, a 100 percent natural alternative to Phen-Fen.
John's Wort) and a mild stimulant (Ma Huang) are combined to produce the weight loss associated with the Phen-Fen Diet without the unwanted side effects.