pharmacogenomics

(redirected from Pharmacogenomic)
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phar·ma·co·ge·net·ics

(far'mă-kō-jĕ-net'iks),
The study of genetically determined variations in responses to drugs in humans or in laboratory organisms.
Synonym(s): pharmacogenomics

pharmacogenomics

(fär′mə-kō-jə-nō′mĭks)
n. (used with a sing. verb)
The study of inherited variations in genetic factors that influence a patient's metabolic response to a given drug, especially adverse side effects. Also called pharmacogenetics.

pharmacogenomics

The formal study of inherited genetic variations that dictate different drug responses. Pharmacogenomics explores the ways such variations can be used to predict responses to investigational products and plays an increasingly important role in drug discovery.

phar·ma·co·ge·net·ics

, pharmacogenomics (fahr'mă-kō-jĕ-net'iks, -nō'miks)
The study of genetically determined variations in responses to drugs in humans or in laboratory organisms.

pharmacogenomics

The recognition of the fact and significance of human genetic variability in relation to drug action and its application to medical treatment. Genetic variability affects drug absorption, distribution, metabolism and excretion. As a result, many drugs which work very well in some people work poorly in others. At present, the best doctors can do is to prescribe a drug and then wait and see how well the patient responds. Fuller knowledge of pharmacogenomics will, in the future, allow more reliable treatment and avoid expensive waste.

pharmacogenomics

analysis of the effects of GENOMICS on drug responses. This involves all the pharmacologically active genes, how they manifest their variations, how they interact to produce PHENOTYPES, and how these phenotypes affect drug responses. DNA MICROARRAYS/CHIPS should be useful in determining how genetic variation influences individual responses to a given drug or class of drugs. A major aim is to personalize drugs, by adapting them specifically to an individual's own genetic make-up, so that they will be fully efficacious with no side effects.
References in periodicals archive ?
Pharmacogenomic testing identifies specific genetic markers within a patient that can help providers tailor their treatment plans more exclusively to that individual.
GeneSight is the only neuropsychiatric combinatorial pharmacogenomic test validated in multiple, peer-reviewed, published clinical studies.
Sirius Genomics is a drug-enabling company that develops pharmacogenomic (PGx) diagnostics that lead to better patient outcomes through personalized medicine.
Pharmacogenomic data submissions to the FDA: non-clinical case studies Pharmacegenomics 5(5):507-511.
The review of these clinical and scientific data clearly reinforces the benefits of pharmacogenomic testing in aiding medication selection and augmenting patient responses to antidepressant and antipsychotic medications.
GeneSight is a unique pharmacogenomic treatment decision support product that tests for clinically important genetic variants affecting a patient's response to psychiatric medications.
The Asuragen Pharmacogenomic Services Division provides a comprehensive range of molecular services empowering commercial and academic scientists to rapidly acquire a wide range of molecular data.
GeneSight is a unique pharmacogenomic decision support tool that tests for clinically important genetic variants affecting a patient's response to psychiatric medications.
AUSTIN, Texas -- Asuragen Pharmacogenomic Services, a molecular biology and human clinical trials service provider, has received a license from Roche Molecular Systems for clinical gene expression profiling and DNA analysis utilizing Roche's real-time quantitative PCR technology (qRT-PCR, qPCR).
The SAB appointments coincide with the Company's increasing emphasis on cutting-edge pharmacogenomic research and new clinical products that support healthcare providers in medication selection for patients with neuropsychiatric and other disorders.
The Frost & Sullivan research service titled European Personalised Medicine and Pharmacogenomics Market provides an overview of the pharmacogenomic tests, together with the revenues, key market drivers, restraints, and trends in the market.
8, a pharmacogenomic testing program helping behavioral health clinicians select medications for their patients using genetic information, peer-reviewed research and approved drug labeling.