Penile ossification commonly occurs because of Peyronie
's disease, which causes formation of fibrous scar tissue within the penis.
'We are encouraged by the continued emphasis from our partner, Endo, on the importance of patient awareness and future growth initiatives for both of our commercial indications for XIAFLEX, Peyronie
's Disease and Dupuytren's Contracture.
Their scientists have found a drug combination which appears to halt the process of fibrosis which causes Peyronie
's Disease -- a condition that causes penile curvature and inhibits erectile function in men.
In this invited commentary, World's famous expert in Peyronie
's disease (PD) surgery, Tom Lue et al.
I just read one of the articles published today in your health and fitness section on the Tribune newspaper; 'my penis is bent' and I'm concerned that the initial complaint only mentions the penis geometry without any note of pain or painful erections (which is hardly a downplayed symptom as associated with Peyronie
's disease.) I'm curious as to why the complainant was not reassured to a great extent that bent penises are common and sometimes 'anatomically normal' as a degree of curve is not necessarily pathological.
Dexamethasone-cyclophosphamide pulse (DCP) therapy was introduced by Pasricha and Gupta in 1982 to treat Reiter's disease.1 Subsequently, it was used to treat pemphigus,2-4 SLE,5 systemic sclerosis,6,7 pyoderma gangrenosum,8 lichen amyloidosis,9 Peyronie
's disease,10 prurigo nodularis11 and also rheumatoid arthritis.12 This paper reports 5 patients of bullous pemphigoid treated with DCP therapy.
's disease was diagnosed in three patients (14.29%) with plaques in tunica albuginea, which were visible in gray scale and palpable on lateral and anterior surface, but no characteristic abnormal curvature of the penis or discomfort during Doppler evaluation noted.
After analyzing health insurance claims from over 1.7 million men, and following up over a span of nine years, researchers found a link between men with Peyronie
's disease--a disorder of the connective tissue in the penis that creates a visible curve in the shaft--and several kinds of cancers.
Differential Diagnoses that must be entertained include penile fracture, Peyronie
's disease, and sclerotizing lymphangitis.
Men with Peyronie
's disease should be monitored for the development of cancer, researchers from Baylor College of Medicine in Texas, U.S.