Peyer's patches


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Peyer's patches

one of a group of solitary nodules or groups of lymph nodes forming a single layer in the mucous membrane of the ileum opposite the mesenteric attachment. They are oval patches about 1 cm wide that extend for about 4 cm along the intestine. In most individuals they appear in the distal ileum, but they also appear in the jejunum of a few individuals.

Peyer's patches

oval, elevated patches of closely packed lymph follicles in mucous and submucous layers of the small intestine. Called also aggregated lymphatic nodules.

continuous Peyer's patches
found in the terminal ileum in calves, lambs, piglets. Thought to be a primary site for B-cell generation; involute with age.
References in periodicals archive ?
The role of Peyer's patches in the age-related incidence of Crohn's disease.
1977) Sequential uptake of horseradish peroxidase by lymphoid follicle epithelium of Peyer's patches in the normal unobstructed mouse intestine: an ultrastructural study.
By ISH analysis, abundant cytoplasmic viral nucleic acid was detected in macrophages within germinal centers and subcapsular and medullary sinuses of the mesenteric lymph nodes from all 4 dogs (Figure 2, panel H), mandibular lymph nodes from 2 dogs, ileal Peyer's patches from all 4 dogs (Figures 2, panels D, F), ellipsoids (terminal arterioles) of the spleen for 1 dog, and germinal centers in splenic white pulp for 2 dogs.
In the present study, one boar had diarrhea and also PCV2 antigen in Peyer's patches, but without any macroscopic changes suggestive of PE.
Function of orally applied immunostimulants seems to be mediated by activation of Peyer's patches of the intestinal immune system (Bodinet et al.
However, in the case of nanoparticles the absorption of nanoparticles takes place via Peyer's patches region, reaches lymphatic system, bypasses the first pass metabolism (bypasses liver: degradation of insulin is significantly reduced) and particles will be degraded and delivers the insulin in the blood stream.
In contrast to the peptide hormone delivery vehicles, however, the Macromune formulation is designed to gain preferential access to the M cells of the Peyer's patches located in the lower small intestine and is thus able to interact with the mucosal immune system and stimulate either a local or a systemic immune response to incorporated antigens.
Stimulation and immune tutoring via the Peyer's Patches in the upper GI.
Since 70% of our immune system emanates from the bowel and Peyer's patches (Figure 2) make 90% of our T lymphocytes, it is important to prepare the soil with care.
The percentage of Fas-receptor (Fas+) and Fas-ligand positive (FasL+) lymphocytes was enhanced in Peyer's patches after exercise.
The IgA receptor has been found to be located on M cells of Peyer's patches in the human intestine, and the receptor contributes to the uptake of antigen-IgA immune complexes into Peyer's patches (Mantis et al.