Peyer patch

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Peyer patch

(pī′ĕr)
[Johann Conrad Peyer, Swiss anatomist, 1653–1712]
A group of diffuse lymphoid nodules in the mucosa of the small bowel. Part of the mucosa-associated lymphoid tissue (MALT), Peyer's patches detect and respond to foreign antigens in the gastrointestinal tract. Antibodies secreted by B cells in Peyer's patches provide a significant defense against ingested pathogens.
References in periodicals archive ?
(1974) Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles.
indicate that fructan supplementation would increase cell number and composition in Peyer's patches, and cause some immunological effects (Watzl et al.
The effect of T-2 toxin on percentages of CD4+, CD8+, CD4+ CD8+ and CD21+ lymphocytes, and mRNA expression levels of selected cytokines in porcine ileal Peyer's patches. Pol.
Gut-associated lymphoid tissues of young swine with emphasis on dome epithelium of aggregated lymph nodules (Peyer's patches) of the small intestine.
Bacteroides induce higher IgA production than Lactobacillus by increasing activation-induced cytidine deaminase expression in B cells in murine Peyer's patches. Biosci Biotechnol Biochem.
Antigen-induced, tolerogenic CD11c+, CD11b+ dendritic cells are abundant in Peyer's patches during the induction of oral tolerance to type II collagen and suppress experimental collagen-induced arthritis.
(2009) CXC chemokine ligand 12 promotes CCR7-dependent naive T cell trafficking to lymph nodes and Peyer's patches. J.
Hypertrophic Peyer's patches of the terminal ileum being responsible for idiopathic intussusception in the ileocolic area.
Microscopy experiments showed that Wellmune was found very close to macrophages and dendritic cells in the Peyer's Patches. Wellmune was also shown to be taken up through the villi, structures which make up the majority of the large and small intestines.
It consists of discrete organs: Peyer's patches (PPs), appendix, and isolated lymphoid follicles (ILFs).
Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. J Exp Med 1994;180:7-9.
Hyperplasia of the intestinal Peyer's patches have been identified as the leading point in infant cases.