Peyer's patches

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Peyer's patches

one of a group of solitary nodules or groups of lymph nodes forming a single layer in the mucous membrane of the ileum opposite the mesenteric attachment. They are oval patches about 1 cm wide that extend for about 4 cm along the intestine. In most individuals they appear in the distal ileum, but they also appear in the jejunum of a few individuals.

Peyer's patches

oval, elevated patches of closely packed lymph follicles in mucous and submucous layers of the small intestine. Called also aggregated lymphatic nodules.

continuous Peyer's patches
found in the terminal ileum in calves, lambs, piglets. Thought to be a primary site for B-cell generation; involute with age.
References in periodicals archive ?
1982) In vivo immune response to a T-cell-dependent antigen by cultures of disassociated murine Peyer's patch.
1982) An enzymatic method for preparation of dissociated murine Peyer's patch cells enriched for macrophages.
For in vivo experiments, suspensions of Peyer's patch cells in RPMI-1640 medium (Gibco, Grand Island, NY) supplemented with 5% fetal bovine serum (FBS) (RPMI 1640-FBS) were prepared from a small intestine of C3H/HeJ mice (female, 6-8 weeks old, SLC, Japan), who had been orally administrated with F-5 (150 mg/kg/day) or distilled water (control) for 1 week.
After F-5 (150 mg/kg/day) was orally administered to C3H/HeJ mice for 1 week, in vivo intestinal immune system modulating activity of orally administered F-5 was evaluated by using the Peyer's patch cells prepared from the mice after 1 day of the final administration of F-5.
Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell T cell mixtures.