econazole

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econazole

[ĕ-kon´ah-zōl]

an imidazole derivative used as the nitrate salt as a broad-spectrum antifungal agent, applied topically in the treatment of cutaneous candidiasis and various forms of tinea.

econazole

(ĭ-kŏn′ə-zōl′)

A broad-spectrum antifungal agent used in the treatment of athlete's foot and related fungal infections.

econazole

A broad-spectrum antifungal drug used in local (topical) application. Brand names are Ecostatin, Pevaryl, Pevaryl TC and Gyno-Pevaryl.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antifungal agent

Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.

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Other key brands include the leading antipruritics brand Foille by Sanofi-Aventis, Pevaryl by Janssen-Cilag, which is present in both topical antifungals and vaginal antifungals, and Proctolyn by Recordati, which is the top ranking brand in haemorrhoid treatments.

Dermatologicals in Italy - New Study Released

The leader was followed by Janssen-Cilag AG, which was present with three major brands: Pevaryl (topical antifungals and medicated shampoos), Daktarin (topical antifungals) and Regaine (hair loss treatments).

Just Published: "Dermatologicals in Switzerland"

Further divestitures: In Italy, the combination of J&J's antifungal creams, Daktarin, Pevaryl and Nizoral, and PCH's Trosyd, would bring the number of producers down from three to two.