pethidine


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me·per·i·dine hy·dro·chlor·ide

(mĕ-per'i-dēn hī'drō-klōr'īd),
A widely used narcotic analgesic.
Synonym(s): pethidine

pethidine

(pĕth′ĭ-dēn′, -dən)

pethidine

A synthetic narcotic painkilling drug somewhat less powerful than morphine. Pethidine is widely used during childbirth and as a PREMEDICATION. Overuse may lead to addiction. The drug is on the WHO official list. A brand name of pethidine in a formulation with promethazine is Pamergan P100.
References in periodicals archive ?
The result of our study shows that pethidine does not have a preemptive analgesic effect like ketamine.
"Intravenous remifentanil PCA halved the proportion of epidural conversions compared with intramuscular pethidine," the authors write.
Pethidine as compared to morphine produce lesser side effects at therapeutic doses.
oleracea II Test 200 3.90 [+ or -] 0.06 III Test 400 3.75 [+ or -] 0.05 IV Test 600 3.85 [+ or -] 0.02 V Standard 5 (i.p.) 3.78 [+ or -] 0.07 (Pethidine) One way ANOVA F 2.337 d.f.
Piperidine ring containing compounds like Pethidine, fantanyl, inovan, ketobemidon, bemidone and a variety of molecules are the result of these efforts [44].
We searched the same database as that mentioned above for the terms pethidine, meperidine, normeperidine, and norpethidine; each search term was combined with the same terms as for lidocaine.
There have not been many reports of such a reaction in published materials, and we take this opportunity to provide further pictorial evidence of the possible sequelae of IV administration of a high concentration Pethidine solution.
Elhakim et al (6) found out that inclusion of low dose pethidine in lidocaine (lignocaine) for tonsillar infiltration improves pain relief following tonsillectomy in children.
Chestnutt24 had also studied effects of nalbuphine, pethidine and placebo and noticed excellent control of haemodynamic response in minor gynaecological surgery in nalbuphine as well as pethidine group, but noticed nausea and vomiting at the end of surgery which was more in pethidine group.
Currently, pethidine is the only controlled drug able to be prescribed by midwives but this may be expanded to a choice of three: pethidine, fentanyl and morphine.
An advantage to using remifentanil, an opioid similar to pethidine, is that it is fast-acting, typically cycling within 3 minutes.
Pethidine HCl (Aldolan 100 mg 2 [mL.sup.-1], Gerot) was administered 0.5 mg [kg.sup.-1] intravenously as a rescue analgesia if the NRS value was >4.