A rare, congenital anomaly of the anterior segment of the eye. It is characterized by a central corneal opacity, usually accompanied by the adhesion of strands of iris tissue to the margins of the opacity, thinning of the stroma and attenuation or absence of Descemet's membrane. A variant of Peter's anomaly (called type 2) presents in addition to the above, either a displacement or a lack of transparency of the lens, which may even become adherent to the posterior surface of the cornea. It is frequently associated with glaucoma. Syn. anterior chamber cleavage syndrome. See Axenfeld's syndrome; Rieger's syndrome.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann