persistent hyperplastic primary vitreous

Also found in: Acronyms.

vitreous, persistent hyperplastic primary (PHPV) 

A congenital, abnormal vitreous development characterized by a retrolental mass formed by remnants of the hyaloid system and tunica vasculosa lentis. The eye presents with leukocoria and there may also be cataract and congenital glaucoma. Treatment should begin as early in life as possible to avoid the risk of damage to the globe and amblyopia. See hyaloid artery; hyaloid remnant.
References in periodicals archive ?
Persistent hyperplastic primary vitreous of the eye: Imaging findings with pathologic correlation.
Persistent Hyperplastic Primary vitreous Magnetic Resonance Imaging and Clinical findings.
Ocular examination should include assessment of visual function, nystagmus, strabismus, the presence or absence of a red pupillary reflex, IOP, corneal diameter and co-existing ocular conditions such as persistent hyperplastic primary vitreous and coloboma (see later).

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