peptidyl transferase

(redirected from Peptidyl transfer)

peptidyl transferase

The enzyme that catalyzes the formation of PEPTIDE BONDS during the synthesis of a polypeptide (translation).
References in periodicals archive ?
# Inhibits peptidyl transfer, blocks P-site interactions, and prevents the normal formation of active 50S ribosomal subunits.
This book is a compilation of articles on significant events in the history of biochemistry, which were published in the journal "Trends in Biochemical Sciences." Editor Witkowski has selected articles that present an insider's view of discoveries that are now seen as landmark achievements, and that relate to the central dogma of molecular biology, which is that DNA makes RNA makes protein, or, "once information has passed into protein it cannot get out again." The book begins with Albrecht Kossel and the discovery of histones, and ranges through Schrodinger and the origins of molecular biology, the double helix, DNA replication, protein synthesis, genetic code, tRNA, mRNA, early ribosome research, peptidyl transfer, and finally to the advent of rapid DNA sequencing.

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