peptidoglycan

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Related to Peptidoglycans: murein, Proteoglycans

peptidoglycan

 [pep″tĭ-do-gli´kan]
a glycan (polysaccharide) attached to short cross-linked peptides; found in bacterial cell walls.

pep·ti·do·gly·can

(pep'ti-dō-glī'kan),
A compound containing amino acids (or peptides) linked to sugars, with the latter preponderant. Compare: glycopeptide.
Synonym(s): mucopeptide (2)

peptidoglycan

/pep·ti·do·gly·can/ (pep″tĭ-do-gli´kan) a glycan (polysaccharide) attached to short cross-linked peptides; found in bacterial cell walls.

peptidoglycan

(pĕp′tĭ-dō-glī′kən, -kăn′)
n.
A polymer found in the cell walls of prokaryotes that consists of polysaccharide and peptide chains in a strong molecular network. Also called mucopeptide, murein.

pep·ti·do·gly·can

(pep'ti-dō-glī'kan)
A compound containing amino acids (or peptides) linked to sugars, with the latter preponderant.
Compare: glycopeptide

peptidoglycan

a main component of bacterial CELL WALLS. Peptidoglycan consists of molecules of SUGARS: N-acetylglucosamine and N-acetylmuramic acid, linked together in rows (forming the glycan portion of peptidoglycan), and adjacent rows are cross-linked by PEPTIDES (forming the peptide portion of peptidoglycan). Peptidoglycan forms a lattice that surrounds and protects the whole cell. Generally, Gram-positive BACTERIA (see GRAM'S STAIN have many layers of peptidoglycan, forming a thick and rigid layer, while gram-negative bacteria have a thin layer of peptidoglycan.

peptidoglycan

a glycan (polysaccharide) attached to short cross-linked peptides; found in bacterial cell walls and is responsible for their structural rigidity.
References in periodicals archive ?
For decades researchers had searched for peptidoglycan--a mesh-like polymer that forms the cell wall in diverse bacteria--in the bacterial pathogen Chlamydiae peptidoglycan in hopes of studying its structure and synthesis as a path to drug development against a class of bacteria responsible for one in 10 cases of pneumonia in children, as well as more than 21,000,000 cases of the blindness-causing disease trachoma.
PRRs have been reported in bivalves, including a peptidoglycan recognition protein in scallops (Suet al.
Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by Toll-like receptor signaling.
New subjects in the manual include cellular components, such as heparin and chondroitin sulfate, and bacteria-specific lipopolysaccharides and peptidoglycans.
Grossman, 1985) and an envelope composed of peptidoglycans outside its
The pathophysiology of bacterial meningitis includes a process that releases bacterial products such as peptidoglycans, lipoteichoic acid, lipopolysaccharides, and denucleated DNA.
Certain cytokines and peptidoglycans that may stimulate natural immunity.
By grabbing onto the ends of cell wall components known as peptidoglycans, the antibiotic prevents them from linking together and thus weakens the wall's structure.
By hydrolyzing the peptidoglycans of procaryote cell walls, human milk LZ has a bacteriolytic function and plays a role, together with secretory IgA and lactoferrin, in the passive protection of breast-fed newborns (7, 8).
Several phytochemicals including phenolics, phenolcarboxylic acids, alkaloids, flavonoids, glycosides, glycolipids, polysaccharides, peptidoglycans, carbohydrates, amino acids and saponins extracted from plant sources have been reported to posses' hypoglycemic activity (Prabhakar and Doble 2011d).
Activation of the human complement cascade by bacterial cell walls, peptidoglycans, water-soluble peptidoglycan components, and synthetic muramylpeptides--studies on active components and structural requirements.