Pneumolysin do not have this signal peptide sequence
indicating the fact that it is an intracellular protein.
Appendix Figure Al shows the regions that were cut for mass spectrometry analysis and the corresponding peptide sequences
that were identified from each band.
First, how many additional peptide sequences
(and what types) can be confidently identified by generating custom proteogenomics databases.
The deduced amino acid sequence has a 21 aa signal peptide sequence
in the N-terminus, and contained a manganese superoxide dismutase domain (DVWEHAYY), four conserved amino acids responsible for binding manganese H48, H96, D180 and H184 and two N-glycosylation sites NHT and, NLS.
The 44 amino acid heliomicin peptide sequence
within this precursor coincided exactly with the P81544 peptide sequence
, containing the 6 cysteine residues within the CS-[alpha][beta] motif characteristic of this protein family.
Phage clone peptide sequences
were determined and analyzed for linear homology to HIV-1 proteins by local BLAST.
Pancreate is a bioactive peptide sequence
of a naturally occurring human protein that has been shown in preclinical studies to stimulate the growth of new insulin producing islets in the pancreas, resulting in restoration of normal metabolic function and glucose control in the blood.
This peptide sequence
is more typical of the target areas in many S100-binding proteins, considering its length and the net charge.
Additionally the presence or absence of a fatty acid monomer provides considerably less specificity than a peptide sequence
Curacao, Netherlands) has patented a method for improving homogeneity and/or secretion of a recombinant protein of interest expressed in mammalian cells by replacing the endogenous signal peptide sequence
of the DNA encoding the protein of interest with that of human hGH.
This research also reported that the KTTKS peptide sequence
from type I pro-collagen stimulated production of collagen I, III and fibronectin in cell culture.
A high probability score indicates a good match between the unknown peptide sequence
and a sequence in the database.