peptide YY

(redirected from Peptide YY 3-36)

pep·tide YY

(pep'tīd)
A hormone released by the small intestine to signal the brain to stop eating.

peptide YY

An appetite-regulating protein released by L cells of the mucosa of the gastrointestinal tract in response to a meal. It binds to cells in the arcuate nucleus of the brain, decreases the desire to eat, and creates a feeling of fullness.
See also: peptide
References in periodicals archive ?
Ghrelin is a 28 amino acid gastric hormone that is released from the enteroendocrine cells of the stomach and large intestine that stimulates appetite (Cummings and Overduin, 2007; Cummings et al., 2002) and promotes gastric motility (Cummings and Overduin, 2007) whereas peptide YY 3-36 (PYY) is a 36 amino acid peptide secreted from L-cells in the intestinal mucosa that suppresses appetite and gastric emptying (Adrian et al., 1985; Cummings and Overduin, 2007; le Roux and Bloom, 2005).