The
penicillin derivatives are "worth the risk," said lead investigator Meghan Jeffres, Pharm.D., of the department of pharmacy practice at Roseman University of Health Sciences in Henderson, Nev.
Other high-risk antibiotics include
penicillin derivatives, especially amoxicillin-clavulanate, and cephalosporins.
Skin testing is typically conducted with a mixture of
penicillin derivatives that encompass both its major and minor determinants.
However, some individuals using both oral contraceptives and certain oral antibiotics, such as tetracycline and
penicillin derivatives, had significant decreases in the concentration of the contraceptive hormone ethinyl estradiol in their blood and appeared to ovulate, putting them at some risk of pregnancy.
Meanwhile, the most consumed of
penicillin derivatives are ampicillin and amoxicillin trihydrate.
Labels frequently carry brand names you might not recognize--Dynapen, Wymox, and Augmentin, to name a few, are all
penicillin derivatives. Last February the Annals of Allergy printed three tragic accounts of individuals who had known antibiotic allergies.
Penicillin derivatives (Piperacillin/Tazobactam) and carbapenem (Imipenem and Meropenem) are the most sensitive antibiotics covering all the organisms isolated in our study.
