Pearson syndrome

(redirected from Pearson marrow pancreas syndrome)

Pearson syndrome

[MIM #557000] Sideroblastic anemia with marrow cell vacuolization and exocrine pancreatic dysfunction; usually lethal in infancy.

Pearson syndrome

A mitochondrial disease characterized by early onset BM dysfunction leading to pancytopenia & pancreatic failure, which may progress to Kearns-Sayre syndrome. See Mitochondrial disease.

Pearson,

H.A.,
Pearson syndrome - refractory sideroblastic anemia; malabsorption or other pancreatic exocrine insufficiency.
References in periodicals archive ?
There may be well recognised clinical features suggesting specific mitochondrial DNA defect and these include Pearson marrow pancreas syndrome, Wolfram's syndrome, MELAS (Myoencephalopathy, lactic acidosis and stroke like episodes), Kearn-Sayre syndrome and MLASA (Myopathy, lactic acidosis and sideroblastic anemia)3.

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