Recurrent purpura and nephritis may occur in paraproteinemias
Immunotactoid keratopathy: A clinicopathologic case report and a review of reports of corneal involvement in systemic paraproteinemias
. Surv Ophthalmol.
Suspecting some form of paraproteinemias
, subsequent investigations including immunoelectrophoresis and immunofixation of serum proteins were carried out which showed no monoclonal gammopathy.
This is also seen in AVWS secondary to certain paraproteinemias
as described in more detail below.
Hemostatic complications associated with paraproteinemias
. Curr Hematol Rep 2003;2:388-94.
Once diagnosis is reached treatment is generally initiated to target any underlying diseases that include inflammatory bowel disease gammopathies paraproteinemias
leukemias Behcet disease Sweet syndrome hepatitis HIV systemic lupus erythematosus and vasculitides.5
Other causes of peripheral neuropathy, such as diabetes, alcoholism, metabolic diseases, intoxications, hereditary neuropathies, HIV, HTLV 1 or 2, vasculitis, paraproteinemias
and other primary or secondary PNS diseases were also ruled-out.
It is usually associated with paraproteinemias
. Scleromyxedema without monoclonal gammopathy is a rare and atypical variant of lichen myxedematosus.
can develop similar lesions (known as necrobiotic xanthogranuloma) that are associated with elevated blood levels of paraproteins.
Secondary factors that worsen hypertriglyceridemia include poor diet, obesity, alcohol use, diabetes, renal disease, pregnancy, nonalcoholic fatty liver disorder, paraproteinemias
, autoimmune disorders, and certain medications, such as steroids.
La disminucion temprana de la via clasica se puede ver en ciertas paraproteinemias
. En estas situaciones, el consumo de C3 no se ve y la GMN es una manifestacion rara de este desorden.
There is extensive coverage of cancer immunology, immunotherapy, immunopharmacology, and immunological aspects of transplantation, paraproteinemias
, and the lymphoreticular system.