Parapoxvirus

(redirected from Parapoxvirus infection)

Par·a·pox·vi·rus

(par'ă-poks'vī'rŭs),
The genus of viruses (family Poxviridae) that includes the contagious ecthyma of sheep, bovine papular stomatitis, and paravaccinia viruses. They possess the nucleoprotein antigen common to all viruses included in the family but differ from other poxviruses in morphology (for example, virions are smaller and have thicker external coats) and by not multiplying in embryonated eggs.

Parapoxvirus

(par″ă-poks′vī″rŭs) [ para- + poxvirus]
A genus of very large DNA viruses that primarily infect ungulates such as deer and cattle. Transmission to humans occasionally occurs, e.g., when farmers, hunters, and ranchers butcher or dress animals.
References in periodicals archive ?
Parapoxvirus infection of the red squirrel (Sciurus vulgaris).
Parapoxvirus infection occurs through scarified or damaged skin (or occasionally through the oral mucosa), followed by virus replication in keratinocytes (Buttner and Rjiha, 2002; Flamming et al., 2007; Gibs, 1984; Mc Keever et al., 1988).
Parapoxvirus infection was suspected, and the lesion was removed surgically.
Histopathology and microscopy can support a diagnosis of a parapoxvirus infection. PCR can definitively identify orf virus (4) and is available at CDC (telephone: 404-639-4129); clinicians should contact their state health department to request PCR testing.
These results suggest the patients had previous OPXV infections, given that an active parapoxvirus infection was demonstrated in patient 4 and vaccination could be ruled out for patients 10 (a 20-year-old) and 14 (a 24-year-old) based on their age.
Histopathology indicated nonspeciiqc inflammation, but serologic evaluation revealed parapoxvirus IgM >1:160 and IgG of 1:512, consistent with current or recent parapoxvirus infection. All lesions healed spontaneously within 2 weeks.
Negative-stain electron microscopy can confirm a parapoxvirus infection by demonstrating classic ovoid cross-hatched virions (Figure 2) but cannot distinguish orf virus from other parapoxviruses such as paravaccinia (pseudocowpox) virus; serologic testing has the same limitation.
The specialists indicated that the lesions appeared to be typical of parapoxvirus infection. CF interviewed case-patients 1-3 again, and they reported having knife wounds after preparing lambs for the religious feast and seeing lesions on the gums and tongue of 1 lamb.
Parapoxvirus infection in harbor seals (Phoca vitulina) from the German North Sea.
Parapoxvirus infections in New Zealand farmed red deer (Cervus elaphus).