paraneoplastic cerebellar degeneration

(redirected from Paraneoplastic neurological disorder)

paraneoplastic cerebellar degeneration

the most common paraneoplastic syndrome affecting the brain, occurring most commonly with ovarian and breast carcinoma and Hodgkin's disease, characterized pathologically by severe loss of Purkinje's cells and clinically by insidious and progressive truncal and appendicular ataxia, dysarthria, nystagmus, and, occasionally, dementia. In some women with gynecological or breast carcinoma, it is associated with an autoantibody (anti-Yo).
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The 46-year-old has paraneoplastic neurological disorder - a condition of the nervous system that was brought on by an undetected cancer - and he has been in intensive care at Newcastle's Royal Victoria Infirmary for the last 10 months.
At this point we found out he had paraneoplastic neurological disorder caused by cancer.
Paraneoplastic neurological disorder is known to be brought on by cancer cells directly disrupting nerve function, however Craig had not shown any symptoms of cancer up until that point and medics had the task of identifying where the tumour was.

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