paraganglioma

(redirected from Paragangliomas)

paraganglioma

 [par″ah-gang″gle-o´mah]
a tumor of the tissue composing the paraganglia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

par·a·gan·gli·o·ma

(par'ă-gang'glē-ō'mă),
A neoplasm usually derived from the chemoreceptor tissue of a paraganglion, such as the carotid body, or the medulla of the adrenal gland; the latter is usually termed a chromaffinoma or pheochromocytoma.
Farlex Partner Medical Dictionary © Farlex 2012

paraganglioma

An uncommon neuroendocrine tumour often of the head and neck which arises in neural crest and is more common in women; 2 to 9% of carotid body, vagal body and jugulo-tympanic paragangliomas are malignant vs. 25% of those in the larynx. Paragangliomas are part of Carney’s triad (extraadrenal paraganglioma, GIST, pulmonary chondroma), and occur in von Hippel-Lindau syndrome..
 
Clinical findings
Pulsatile mass, tinnitus.

Sites
Carotid body (60%), jugulotympanic, glomus vagale.

DiffDx
Neuroendocrine tumours—e.g., carcinoid, haemangiopericytoma, neuroendocrine carcinoma, medullary carcinoma of thyroid, middle ear adenoma, meningioma.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

paraganglioma

Oncology A head & neck neural crest tumor more common in ♀; 2-9% of PGs in carotid body, vagal body and jugulo-tympanic region are malignant; 25% of laryngeal PGs are malignant. See Zellballen.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

par·a·gan·gli·o·ma

(par'ă-gang-glē-ō'mă)
A neoplasm usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or the medulla of the suprarenal gland; the latter is usually termed a chromaffinoma or pheochromocytoma.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

par·a·gan·gli·o·ma

(par'ă-gang-glē-ō'mă)
A neoplasm usually derived from the chromoreceptor tissue of a paraganglion or the medulla of the suprarenal gland.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Keywords: Carotid body tumors, Harmonic Scalpel, Internal carotid artery reconstruction, Internal carotid artery ligation, Paragangliomas.
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare tumours arising from chromaffin tissues.
Imaging studies for bladder paragangliomas include ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and Molecular imaging scans using radiotracers.
focused on patients, who were born with cyanotic congenital heart disease and went on to develop adrenal gland or related tumors called pheochromocytomas or paragangliomas.
The study focused on patients, who were born with cyanotic congenital heart disease and went on to develop adrenal gland or related tumors called pheochromocytomas or paragangliomas.
Pheochromocytoma (PHEO; MIM #171300) is a rare neuroendocrine tumor of chromaffin cells originating in the adrenal medulla, whereas paragangliomas (PGLs; MIM #168000) are even rarer tumors arising in the paraganglia along the parasympathetic and sympathetic chains [1].
Paragangliomas are rare, slow-growing neuroendocrine tumors arising from cells of neural crest origin.
Duodenal gangliocytic paragangliomas are a subclass of duodenal neuroendocrine neoplasms, ranking third in frequency behind gastrinomas and somatostatinomas of the duodenum, comprising about 10% of those, and most commonly arising from the second portion of the duodenum [3].
Despite this well-known inherited basis of PCCs and paragangliomas (PGLs), during the past decades somatic mutations with variable frequency in many genes, including EPAS1 (HIF2[alpha]), RET, VHL, RAS, NF1, ATRX, and CSDE1 recurrent somatic copy number alterations and several fusion genes, involving MAML3, BRAF, NGFR, and NF1, have been progressively identified [5-16].
Paragangliomas (PG) are rare tumors originating from neural crest cells, arising at various locations along the chain of the sympathetic nervous system as well as the branchiomeric paraganglioma.
No polygonal or columnar cells typically seen in paragangliomas were noted, and the presence of ganglion cells excluded schwannoma and neurofibroma.
Intestinal pseudo-obstruction as a complication of paragangliomas: case report and literature review.