The immunohistochemical demonstration of parafollicular
cells and evaluation of calcium-phosphate balance in patients with thyroid hemiagenesis.
1) C cells are located between the follicular epithelial cells and their basement membranes and, hence, are also referred to as parafollicular
cells, a term first coined by Jose Fernandez Nonidez.
These are follicular cells and parafollicular
Calcitonin, secreted by the parafollicular
cells of the thyroid gland, also acts on calcium concentrations to balance, and oppose, the effects of PTH.
Five pairs of endoderm-lined pharyngeal pouches give rise to the middle ear cavity, auditory tube, tympanic membrane (from the first pair), palatine tonsils (from the second pair), thymus and lower parathyroid glands (from the third pair), upper parathyroid glands (from the fourth pair), and parafollicular
cells of the thyroid gland The subsequent foregut extends to the bottom of the liver bud.
The second group consists of carcinoma arising from parafollicular
cells of ultimobranchial body of neural crest, which is the medullary carcinoma.
This gland consists of thousands of thyroid follicles, vesicular endocrine glands coated by simple cuboidal epithelium and C cells (or parafollicular
The IHC characterization of the thyroid cells was performed with antibodies against thyroglobulin (specific for thyroid follicular cells) and calcitonin (specific for thyroid C-cells [or parafollicular
cells]) (RAMOS-VARA et al.
18,24) Calcitonin, a hormone produced by parafollicular
C cells in the thyroid gland, normally helps in regulation of blood calcium levels.
The second hormone is calcitonin (CT) which originates from the C cells or parafollicular
cells of the thyroid and thymus glands.
were located basally in cluster of 2 or 3 cells.
In the interfollicular area there are a large number of cells, such as fibroblasts and parafollicular
cells ("C" cells), which produce calcitonin.