Paneth cell


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Paneth cell

narrow, pyramidal or columnar epithelial cell with a nucleus close to its base. Found in the fundus of the mucosal crypts in the intestine.
References in periodicals archive ?
We first wish to refer to a family of cationic anti-bacteria peptides known as "defensins": the alpha-defensins released by Paneth cells, and the beta-difensins, as coming from colonocytes.
thetaiotaomicron has been shown to regulate the expression of endogenous protein antibiotic production of Ang4 by Paneth cells (32-34).
In the small intestine, so-called Paneth cells normally secrete antimicrobial compounds (SN: 8/26/00, p.
Defensins: Small proteins secreted by paneth cells that mediate defense against harmful microbes.
Until now, there has been no good way to grow large numbers of these stem cells, because they only remain immature while in contact with a type of supportive cells called Paneth cells.
Paneth cell granule depletion in the human small intestine under infective and nutritional stress.
Long known as Paneth cells, these sentries inhabit tiny pits in the intestine called crypts.
This rectal biopsy shows surface epithelial injury, a mild increase in the number of inflammatory cells in the lamina propria, and prominent subepithelial collagenous band in a background of crypt distortion and Paneth cell metaplasia.
In developing mice, Paneth cell granules were positive for PhloxineTartrazine stain only at 7th postnatal day (4).
Paneth cell metaplasia may be a marker of CC that is more refractory to therapy.
20) Skip lesions, neural hypertrophy, Paneth cell metaplasia, and pyloric gland metaplasia have not been observed in MCD.
NOD-2 is found on Paneth cells that sense bacterial residues, dendritic cells, and macrophages.