pancuronium bromide

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pan·cu·ro·ni·um bro·mide

(pan-kyū-rō'nē-ŭm brō'mīd),
A nondepolarizing steroidal neuromuscular blocking agent resembling curare.

pancuronium bromide

a skeletal muscle relaxant; a nondepolarizing neuromuscular blocker.
indications It is prescribed as an adjunct to anesthesia and mechanical ventilation.
contraindications Known hypersensitivity to this drug or to other bromides prohibits its use. Ventilation always must be supported during the use of neuromuscular blockers. Patients with renal and hepatic disease require dosage adjustments, and pancuronium is not recommended during pregnancy. Some diseases (e.g., myasthenia gravis) can potentiate the effects of pancuronium, whereas others (e.g., diabetes mellitus) can antagonize the drug's effects.
adverse effects The most serious adverse effects are prolonged muscle relaxation and respiratory depression.

pancuronium bromide

A neuromuscular blocking agent.

pancuronium bromide, (pang´kyərō´nēəm brō´mīd),

n a skeletal muscle relaxant prescribed as an adjunct to anesthesia and mechanical ventilation.
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References in periodicals archive ?
Supreme Court ruled that the three-drug execution cocktail used by Oklahoma - midazolam, pancuronium bromide and potassium chloride - does not constitute cruel and unusual punishment.
Supreme Court approved a three-drug combination of (1) sodium thiopental, a sedative that induces unconsciousness, (2) pancuronium bromide, a muscle relaxer that induces paralysis, stopping respiration, and (3) potassium chloride, which causes cardiac arrest.
Traditionally, lethal injection has been carried out with a cocktail of three drugs – sodium thiopental which knocks the victim unconscious, pancuronium bromide which causes paralysis and stops breathing, and, nally, potassium chloride to stop the heart.
An Oklahoma coroner suggested the three-drug protocol: sodium thiopental, to put the inmate to sleep; pancuronium bromide, to induce paralysis; and potassium chloride, to quickly stop the heart and cause death.
Last Tuesday, the day before Hill was initially scheduled to die, the prison system announced it was abandoning its usual drug protocol -- a sedative followed by the paralytic pancuronium bromide and then potassium chloride, which stops the heart -- to using a single drug, the barbiturate pentobarbital.
In 1 study in kestrels (Falco tinnunculus), the mydriatic effect of topical administration of 3 different NMBAs (alcuronium chloride, pancuronium bromide, and vecuronium bromide) was evaluated.
Second, he received an injection of pancuronium bromide, a muscle relaxer.
Suppliers of the three most common drugs - sodium thiopental, pancuronium bromide and potassium chloride - are facing stiff international pressure to stop the deadly trade.
Alavi sold 150 vials of sodium thiopental, 180 vials of potassium chloride, and 450 vials of pancuronium bromide to the Arizona State Prison on September 28th, 2010.
A tiny pharmaceutical company with its head office in the ELgone Driving Academy sold enough sodium thiopental, pancuronium bromide and potassium chloride to Arizona and California last October to end the lives of 10 death row inmates.
a company run from a London driving school office, shipped sodium thiopental, potassium chloride and pancuronium bromide in September.
In contrast to the effect of atropine, the TDE-induced reduction in Schaffer collateral fEPSPs persisted despite pretreatment of the slices with pancuronium bromide (100 [micro]M).