Pancoast's tumourAny tumour situated in the lower part of the neck which, because of its location, involves certain structures to cause a characteristic group of physical signs. These may include pain in and around the region caused by spread of the tumour to the lung covering (pleura) the ribs and the spine; weakness in the arm from damage to nerves in the armpit; hoarseness of the voice due to involvement of the nerves to the LARYNX; and HORNER'S SYNDROME from damage to the sympathetic chain of nerves in the neck. Pancoast's tumour is commonly an advanced lung cancer (bronchial carcinoma). (Henry Khunrath Pancoast, 1875–1939, American radiologist).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005