pamidronate

pamidronate

 [pam″ĭdro´nāt]
an inhibitor of bone resorption, used to treat malignancy-associated hypercalcemia, Paget's disease of bone, and osteolytic metastasis secondary to breast cancer or myeloma; used as the disodium salt. Complexed with technetium 99m it is used in bone imaging.

pamidronate

/pam·i·dro·nate/ (pam″ĭ-dro´nāt) an inhibitor of bone resorption used to treat malignancy-associated hypercalcemia, osteitis deformans, and osteolytic metastasis secondary to breast cancer or myeloma; used as the disodium salt. Complexed with technetium 99m, it is used in bone imaging.

pamidronate

Aredia® Metabolism A 2nd-generation biphosphonate used to manage osteoporosis and Paget's disease of bone. See Biphosphonate, Osteoporosis.

pamidronate

A BISPHOSPHONATE drug that prevents bone reabsorption by interfering with the action of osteoclasts. The drug has been used to treat cancer bone metastases and MULTIPLE MYELOMA. A brand name is Aredia.
References in periodicals archive ?
Contract notice: provision of anticancer drugs, hormone therapy, octreotide and sodium pamidronate
The patient was prescribed celecoxib (200 mg/day), low-dose prednisolone (10 mg/day), and pamidronate (60 mg/month) to control the swelling and periostitis.
Pamidronate treatment improves bone mineral density in children with Menkes disease.
Several therapies have been excluded from the update, including calcitonin, which is no longer widely used for osteoporosis treatment, and etidronate and pamidronate, neither of which are FDA-approved for the prevention of fractures or treatment of osteoporosis.
Studies using cyclical pamidronate infusions suggest that the bisphosphonate group of drugs may be a clinically effective therapy for affected infants and children [17].
Similarly, it no longer addresses the use of etidronate or pamidronate, which are not approved by the Food and Drug Administration for this indication.
For instance, researchers have evaluated the use of combination drugs, which include pamidronate and calcitonin.
Case Report of spontaneous, nonspinal fractures in a multiple mieloma patient on long-term pamidronate and zoledronicaci.
His hypercalcemia continued to worsen with the initiation of MAI therapy but we were able to treat it successfully with pamidronate and calcitonin.
Pamidronate (Aredia) and zolendronate (Zometa) induced avascular necrosis of the jaws: growing epidemic.
Most potent bisphosphonates such as pamidronate and zoledronic acid are preferred for the treatment of these patients.