PAH

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PAH

Abbreviation for p-aminohippuric acid.

PAH

,

PAHA

aminohippuric acid.

pulmonary hypertension, primary, type 1

A rare disorder (OMIM:178600) characterised by plexiform lesions of proliferating endothelial cells in pulmonary arterioles, leading to elevated pulmonary arterial pressure, right ventricular failure and death. The disease can occur at any age from infancy onward, but has a mean age of onset at 36 years. Cases secondary to known aetiologies are the more common cause of pulmonary hypertension, and include those associated with appetite-suppressant drugs.

Molecular pathology
May be caused by defects of SMAD9, which encodes a receptor-regulated SMAD, transducing signals from TGF-beta family members.

PAH

1. Polycyclic aromatic hydrocarbon, see there.
2. Pulmonary artery HTN.
References in periodicals archive ?
PAH-DNA adduct levels provide an integrated index of biologically effective dose, indicative of both exposure to PAHs from all routes (including both inhalation, dermal absorption, and ingestion) and individual metabolic differences in detoxification (Veglia et al.
The qualitative distribution of non-alkylated PAHs is about the same in most environmental samples.
Stanford graduate student Simon Clemett and Washington University graduate student Scott Messenger said the discovery confirmed observations of scientists who long have believed that their telescopes were picking up chemical signatures resembling PAH compounds in the space between stars.
The researchers used a new, simpler technique that they developed for measuring PAHs in samples of particulate air pollution.
Even though smokeless tobacco use does not involve burning, moist snuff is getting contaminated with PAH during its manufacturing," said Stepanov.
Consequently, developmental exposure to PAHs has the potential to cause adverse health outcomes.
Unfortunately, researchers don't yet know enough to determine if HAs in broiled and other meats pose a greater risk than PAHs in grilled meats.
It found the toxicity levels of PAHs are highest in winters.
The new maps showed that small, electrically neutral, irregularly shaped PAHs are most common near the cold molecular cloud that is far from the star that excites PAH emission.
We successfully analyzed two dust samples for PAHs in 201 homes and successfully analyzed only the second dust sample for PAHs in three homes.
Past research has tied air pollution to asthma and allergy, but the link between PAHs and these immune problems is still unclear.