Paget cells

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Pa·get cells

relatively large, neoplastic epithelial cells (carcinoma cells) with hyperchromatic nuclei and abundant palely staining cytoplasm; in Paget disease of the breast, such cells occur in neoplastic epithelium in the ducts and in the epidermis of the nipple, areola, and adjacent skin.


Sir James, English surgeon, 1814-1899.
extramammary Paget disease - Synonym(s): Paget disease
Paget abscess syndrome - an abscess recurrence at the same site after apparent cure.
Paget associated osteogenic sarcoma
Paget cells - relatively large neoplastic epithelial cells.
Paget disease - an intraepidermal form of mucinous adenocarcinoma, most commonly in the anogenital region. Synonym(s): extramammary Paget disease
Paget disease of bone - osteitis deformans. Synonym(s): Paget II syndrome
Paget disease of the nipple - ductal carcinoma.
Paget disease of the penis - carcinoma that develops after balanitis.
Paget juvenile syndrome - Synonym(s): familial osteoectasia
Paget quiet necrosis - necrosis in the superficial layers of the shaft of a long bone.
Paget I syndrome - relationship to or possible extension of mammary duct carcinoma.
Paget II syndrome - Synonym(s): Paget disease of bone
Paget test - to determine whether a mass is a solid tumor or a cyst.
Paget-von Schrötter syndrome - stress thrombosis or spontaneous thrombosis of the subclavian or axillary vein. Synonym(s): effort-induced thrombosis
References in periodicals archive ?
These findings are difficult to reconcile with the consistent coexpression of CK7 and CK20 in the Paget cells in cases of PPD associated with rectal adenocarcinoma if one assumes that the rectal adenocarcinoma is the source of the Paget cells.
Although this cytokeratin profile matches that seen in the Paget cells in cases of PPD associated with a regional internal cancer, it does not appear to be a consistent finding in anal gland carcinoma.
The absence of GCDFP-15 immunoreactivity in these cases distinguishes these Paget cells from the predominant immunophenotype identified in the Paget cells in vulvar Paget disease, which usually represents a primary cutaneous intraepithelial neoplasm in which the Paget cells display sweat gland differentiation.