Paget cell


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Pa·get cell

(paj'ĕt sel)
A relatively large, neoplastic epithelial cell (carcinoma cell) with a hyperchromatic nucleus and abundant palely staining cytoplasm; in Paget disease of the breast, such cells occur in neoplastic epithelium in the ducts and in the epidermis of the nipple, areola, and adjacent skin.
References in periodicals archive ?
Thus, CK7 appears to be a universal marker of Paget cells, regardless of their site or the presence of an associated internal malignancy.
However, lack of E-cadherin immunoreactivity was apparent between Paget cells in which aggregates of 2 or more carcinoma cells were present.