Suprapubic region, Paget's cells, cytokeratin 7, carcinoembryonic antigen.
Dermis showed chronic inflammatory cells with invasion of Paget's cells into the dermis at places (Figure 2 and 3).
The current theories on the origin of Paget's cells are: a) an adenocarcinoma in pluripotent epidermal cells, b) an underlying adenocarcinoma of apocrine or eccrine glands or c) the multicentric effect of a carcinogenic stimulus in the epidermis.