NLRP6

(redirected from PYPAF5)

NLRP6

A gene located on chromosome 11p15 that encodes a cytoplasmic protein of the NALP protein family, which is thought to activate CASP1 and promote activation of NF-kappa-B.
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Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.