PEX19

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PEX19

A gene on chromosome 1q23.2 that encodes a peroxin involved in early peroxisomal biogenesis, which acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins.
  
Molecular pathology
PEX19 mutations cause peroxisome biogenesis spectrum disorder, complementation type 14 and a clinical form of Zellweger syndrome.
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The main inclusion criteria was an existing and detectable pseudoexfoliation syndrome with its characteristic findings in the anterior segment which includes the typical PXF disc with its fluffy deposits on the anterior lens capsule, the transillumination defect on the pupillary borders, and the poor pupillary dilation (maximum pupil diameter 3.5 mm in spite of medical-induced mydriasis).
Results: Mean age of group A (PXF patients) was 65.63 +- 8.47 years and of group B (Healthy subjects) was 64.31 +- 6.51 years (p = 0.470).
However, we have not revealed a significant change in endothelial cell counts, as well as in polymegathism and pleomorphism in patients with PXF compared to those with POAG.
(19) The treatment can also be effective in treating PXF and pigmentary glaucoma.
Glaucoma types classified according to age groups Glaucoma type Patients 40-49 yrs 50-59 yrs CACG 10 2 2 NAG 237 12 26 PDS 151 3 13 POAG 1,348 68 175 Suspect 2,017 343 608 PXF 89 9 16 OHTN 12 1 4 LTG 28 1 9 NVG 35 2 3 Congenital 20 0 0 Juvenile 16 0 0 Totals 3,963 441 856 (11.1%) (21.6%) Glaucoma type 60-69 yrs 70-79 yrs CACG 6 0 NAG 11 188 PDS 39 96 POAG 391 714 Suspect 881 185 PXF 36 28 OHTN 5 2 LTG 11 7 NVG 15 15 Congenital 0 0 Juvenile 0 0 Totals 1,395 1,235 (35.2%) (31.1%) Table 3.
The purpose of the present study was to evaluate whether KBG has an effect on RBC deformability in comparison with pentoxifylline (PXF).
The Cisco Route Processor module is a seamlessly integrated IP services gateway for Cisco AAMP, utilizing the Cisco IOS software and powered by the Cisco PXF adaptive processing for highest performance.
Any pupillary abnormalities (posterior synechia, mid dilated pupil status, sphincter atrophy, PXF, etc) should be documented for decision making at a later stage.
The proceeds from the new notes will be used (i) to repay around USD1,070 million of outstanding notes due 2021, (ii) reduce the notional amount outstanding under the pre-export finance (PXF) facility to USD765 million, (iii) pay for transaction costs of the refinancing and (iv) contribute USD90 million additional liquidity for Metinvest's operational requirements.
More recently, microinvasive glaucoma surgery has emerged as a new treatment for open-angle glaucoma (OAG) including pseudoexfoliative glaucoma (PXF) and pigmentary glaucoma (PG).