treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology.
Efficacy of concomitant use of PUVA
and methotrexate in disease clearance time in plaque type Psoriasis.
reported that both PUVA
and UVB phototherapy are useful alternatives in the treatment of the disease by a comparative prospective study.
Standard therapeutic modalities include phototherapy (ultraviolet B (UVB), combined ultraviolet A (UVA) and UVB wave), photochemotherapy (UVA--with systemic photosensitizer--PUVA), combination of retinoids and PUVA
(Re-PUVA), cytotoxic therapy, retinoids, antibiotic and biological therapy [24-27].
Other risk factors for melanomas include three or more blistering sunburns before age 18 years, congenital nevi, large numbers of moles, and long-term phototherapy for eczema or psoriasis with psoralens and UVA (PUVA
Topical treatments Topical steroids Intralesional steroid injections Topical contact sensitizers Anthralin Minoxidil Topical retinoids Tacrolimus Systemic treatments Systemic corticosteroids Sulfasalazine Azathioprine Methotrexate Oral zinc sulphate Photo-and photochemotherapy PUVA
NBUVB Excimer laser Miscellaneous and Non-pharmacological treatment Dermatography, wigs Hypnotherapy etc Topical treatment options
"Treatment options, depending upon many factors, include corticosteroids, PUVA
, Narrow-band UVB phototherapy, topical tacrolimus, laser treatments, skin grafting, transplantation of cultured melanocytes, and de-pigmentation."
NB-UVB(311) is used as a phototherapy in a number of dermatology departments as an alternative to broad-band UVB (270-350 nm) or psoralen plus UVA (PUVA
--PUVA THERAPY--Photochemotherapy with 8 methoxypsoralen and long-wave ultraviolet light (PUVA
) has been used successfully in the treatment of skin lesions and cu-taneous lichen planus.