ATIC

(redirected from PURH)

ATIC

A gene on chromosome 2q35 that encodes a bifunctional protein that catalyses the last two steps in purine biosynthesis.

Molecular pathology
ATIC mutation causes AICA-ribosiduria.
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References in periodicals archive ?
Rouen: Publcations des Universites de Rouen et du Havre - PURH.
2008) showed that the expression of apoB and PURH genes in liver changed after selection for egg production.
We demonstrated that both apoB and PURH were more highly expressed in the liver than that in other tissues (muscle, ovary, and oviduct) in laying Taiwan Country chickens.
The PURH transcript was also highly expressed in the liver and to a much lesser extent in the ovary of laying Taiwan Country chickens (Figure 2).