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Acronym for pruritic urticarial papules and plaques of pregnancy, an intensely pruritic, occasionally vesicular, eruption appearing in the third trimester of pregnancy, without effect on the fetus; spontaneous involution occurs within 10 days of term, and recurrence is rare in subsequent pregnancies. Negative lesional immunofluorescence microscopy helps to exclude herpes gestationis.
Farlex Partner Medical Dictionary © Farlex 2012

toxic erythema of pregnancy

A dermopathy that affects about 1:200 pregnancies, which presents as an intensely pruritic wave of papules and urticarial plaques, with scattered vesicles, over the lateral abdominal wall during the last few weeks of pregnancy, often extending to the trunk and limbs whilst sparing the umbilical region. The lesion resolves with delivery or shortly thereafter.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Obstetrics Pruritic urticarial plaques and papules of pregnancy An erythematous papule and plaque-forming eruption seen late in the 3rd trimester in up to 75% of primigravidas, which does not recur in subsequent pregnancies Treatment Topical steroids. See Pruritus gravidarum.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

pru·rit·ic ur·ti·car·i·al pap·ules and plaques of preg·nan·cy

(PUPPP) (prūr-it'ik ŭr'ti-kar'ē-ăl pap'yūlz plaks preg'năn-sē)
Intensely pruritic papulovesicles that begin on the abdomen in the third trimester and spread peripherally, resolve rapidly after delivery, and do not affect the fetus.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Pruritic urticarial papules and plaques of pregnancy: Polymorphic eruption of pregnancy (PUPPP).Clin Dermatol.
They include polymorphic eruption of pregnancy (PEP), formerly known as pruritic urticarial papules and plaques of pregnancy (PUPPP); pemphigoid gestationis (PG), formerly known as herpes gestationis; intrahepatic cholestasis of pregnancy (ICP); and atopic eruption of pregnancy (AEP).AEP includes eczema of pregnancy(EP), prurigo of pregnancy(PP) and pruritic folliculitis(PF).
Pruritic urticarial papules and plaques of pregnancy (PUPPP) is benign self-limiting pruritic inflammatory disorder that usually affects primigravida in the last weeks of pregnancy or immediately postpartum.3 Also known as toxemic rash or polymorphic eruption of pregnancy.
This distribution helps to differentiate PUPPP from PG, where the lesions typically cluster around the umbilicus.
As the name implies, the lesions of PUPPP are itchy, red papules that often coalesce into plaques (FIGURE 2).
This condition is known by many names besides PUPPP: polymorphic eruption of pregnancy, toxemic erythema of pregnancy, and late prurigo of pregnancy.
As the name suggests, the lesions of PUPPP are itchy, red papules that often coalesce into plaques (FIGURE 2, page 28).
(12) Another hypothesis is that increased levels of fetal DNA that have been detected in the skin of PUPPP patients may contribute to the pathology.
PUPPP can be diagnosed only by clinical observation.
Polymorphic Eruption of Pregnancy (PEP): (Syn: Pruritic Urticarial Papules and Plaques of Pregnancy or PUPPP, Bourne's Toxaemic Rash of Pregnancy, Toxic Erythema of Pregnancy, Nurse's Late Prurigo of Pregnancy)