PUM1

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PUM1

A gene on chromosome 1p35.2 that encodes a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. PUM1 may support stem cell proliferation and self-renewal by regulating translation of key transcripts. It is expressed in the brain, heart, kidneys, muscle, intestine and stomach and downregulated in keratinocytes in response to UVB irradiation.
References in periodicals archive ?
Supper adds, "Through our affiliation with ACTS, we have significantly more buying power than the four facilities chat were PUMH.
The contracts of new PUMH residents moving in post-affiliation also changed to ACTS contracts.
On an aggregate basis, PUMH has a total of 482 ILUs, 147 ALUs and 151 SNF beds.
The Stable Outlook reflects Fitch's belief that PUMH will renew or replace the existing LOC commitment and maintain strong profitability and debt service coverage which mitigates the concerns of light liquidity.
While not required to provide annual disclosure under the series 2007 bond documents, PUMH through ACTS provides quarterly and annual disclosure which includes a balance sheet, income statement and statement of cash flows as well as utilization statistics and various ratio calculation through the Municipal Rule Making Board's EMMA system.